Certified Hemodialysis Technician Practice Exam 2025 - Free Hemodialysis Technician Practice Questions and Study Guide

Beta2-microglobulin is a small protein that is typically excreted by the kidneys. In patients with kidney failure, the ability to filter and excrete this protein is impaired. As a result, beta2-microglobulin can accumulate in the body, leading to a condition called amyloidosis, where abnormal protein deposits form in various tissues and organs. This accumulation is particularly associated with dialysis patients and can contribute to various complications, including bone, heart, and joint issues.

The other conditions listed do not directly relate to the accumulation of beta2-microglobulin. Hyperparathyroidism is more commonly associated with calcium and phosphate imbalance resulting from chronic kidney disease rather than protein build-up. Diabetes insipidus is a disorder related to the regulation of water, primarily involving the hormone vasopressin, and is unrelated to the excretion of beta2-microglobulin. Metabolic acidosis relates to an overall imbalance of acids and bases in the body, frequently seen in kidney failure, but it does not stem specifically from the failure to excrete beta2-microglobulin.

The link between beta2-microglobulin accumulation and amyloidosis highlights the importance of monitoring protein levels and managing kidney function in patients with renal